Pharmaceutical safety dosage forms

A - Human Necessities – 61 – K

Patent

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A61K 9/00 (2006.01)

Patent

CA 2735280

The invention provides a pharmaceutical safety dosage form comprising a pharmaceutical and an antagonist for said pharmaceutical wherein said antagonist comprises an emetic agent and has bioavailability only when said pharmaceutical safety dosage form is disrupted, and wherein the pharmaceutical is a blood pressure-lowering agent and the antagonist optionally further comprises a sympathomimetic. The invention also provides a pharmaceutical safety dosage form comprising a pharmaceutical and an antagonist for said pharmaceutical wherein said antagonist has bioavailability only when said pharmaceutical safety dosage form is disrupted, and wherein the pharmaceutical is a blood pressure-lowering agent and the antagonist is a sympathomimetic. The pharmaceutical safety dosage forms of the present invention are useful for providing pharmaceutical ingredients in forms which can minimize the effects of abusive or otherwise inappropriate use of the pharmaceutical ingredients.

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