Treatment of tumors with acetylenes distributed with a...

A - Human Necessities – 61 – K

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A61K 31/4436 (2006.01) A61K 38/21 (2006.01) A61P 35/00 (2006.01) A61P 35/02 (2006.01)

Patent

CA 2418988

Compounds of the Formula (1) where the symbols have the meaning described in the specification, and particularly the compound of the Formula (3) exhibit synergistic anti-proliferative effect with human recombinant interferon in the treatment of solid tumors and leukemia, particularly breast cancer and acute myeloid leukemia.

L'invention concerne des composés représentés par la formule (I), dont les symboles sont tels que définis dans la description. Plus particulièrement, le composé représenté par la formule (3) présente une activité anti-proliférative synergique avec l'interféron recombinant humain dans le traitement de tumeurs solides et de la leucémie, et notamment dans le traitement du cancer du sein et de la leucémie myéloïde aiguë.

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