2-(3,5-bis-trifluoromethyl-phenyl)-n-methyl-n-(6-morpholin-4...

Details 2-(3,5-bis-trifluoromethyl-phenyl)-n-methyl-n-(6-morpholin-4... 2-(3,5-bis-trifluoromethyl-phenyl)-n-methyl-n-(6-morpholin-4...

C - Chemistry, Metallurgy

07

D

C07D 213/75 (2006.01) A61K 31/5377 (2006.01) A61P 11/06 (2006.01) A61P 19/02 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2326529

The invention relates to the compound of the formula (see formula I) which is 2-(3,5-bis-trifluoromethyl-phenyl)-N-methyl-N-(6-morpholin-4-yl-4-o- tolyl- pyridin-3-yl)-isobutyramide. It has been found that this compound has a high affinity to the NK- 1 receptor and it is therefore useful in the treatment of diseases, which relate to this receptor.

Cette invention porte sur le composé de formule (voir formule I) qui est 2-(3,5-bis- trifluorométhyl-phényl)-N-méthyl-N-(6-morpholine-4-yl-4-o-tolyl-pyridin-3-yl) isobutyramide. On a constaté que ce composé possède une affinité élevée pour le récepteur NK-1 et il est donc utile dans le traitement des maladies, qui se rapportent à ce récepteur.

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