Celecoxib prodrug

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 233/54 (2006.01) A61K 31/415 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2505635

N-[[4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]- sulfonyl]propanamide and pharmaceutically acceptable salts thereof are useful prodrugs of the selective COX-2 inhibitory drug celecoxib, which can be administrated to a subject by any suitable route.

L'invention concerne le N-[[4-[5-(4-méthylphényl)-3-(trifluorométhyl)-1H-pyrazole-1-yl]phényl]-sulfonyl]propanamide et ses sels pharmaceutiquement acceptables, utilisés en tant que promédicaments du médicament celecoxib inhibiteur sélectif de la COX-2, qui peut être administré à un sujet par une voie appropriée.

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