Process for concentration of antibodies and therapeutic...

Details Process for concentration of antibodies and therapeutic... Process for concentration of antibodies and therapeutic...

C - Chemistry, Metallurgy

07

K

C07K 1/34 (2006.01)

Patent

CA 2577317

The present disclosure provides a process for concentrating proteins including an ultrafiltering, a diafiltering, and a second ultrafiltering sequence, at elevated temperatures, such as above about 30~C. The disclosure also includes a process for preparing highly concentrated antibody compositions, and highly concentrated antibody products.

L'invention concerne un procédé pour concentrer des protéines comprenant une première séquence d'ultrafiltration, une séquence de diafiltration, et une deuxième séquence d'ultrafiltration, à des températures élevées, par exemple supérieures à 30 °C. Cette invention se rapporte en outre à un procédé pour préparer des compositions d'anticorps hautement concentrées, et des produits d'anticorps hautement concentrés.

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