A - Human Necessities – 61 – L
Patent
A - Human Necessities
61
L
A61L 15/44 (2006.01) A61L 17/00 (2006.01) A61L 27/54 (2006.01) A61L 29/16 (2006.01) A61L 31/16 (2006.01)
Patent
CA 2437385
The present invention relates to compositions comprising a combination of one or more antiseptic and an antibiotic. It is based, at least in part, on the discovery that such combinations tend to deter the formation of antibiotic- resistant organisms. In preferred, nonlimiting embodiments of the invention, the antibiotic is minocycline and the antiseptic is a chlorhexidine compound, triclosan, or benzalkonium chloride, and in particular embodiments, a silver salt or a bismuth salt is added. Examples of specific, nonlimiting embodiments of the invention include combinations of (i) minocycline, triclosan, and a bismuth salt; (ii) minocycline, a chlorhexidine compound, and a bismuth salt; and (iii) minocycline, benzalkonium chloride, and a bismuth salt. The present invention further provides for articles, such as, but not limited to, medical articles, which have been treated with or which otherwise comprise a combination of antiseptic and antibiotic.
L'invention concerne des compositions comprenant une combinaison d'un, ou de plusieurs, antiseptique et antibiotique. L'invention repose, au moins en partie, sur le fait que de telles combinaisons tendent à empêcher la formation d'organismes résistant aux antibiotiques. Dans des réalisations préférés, non limitantes, l'antibiotique est de la minocycline et l'antiseptique est un composé chlorhexidine, du triclosan ou un chlorure de benzalkonium, et on y ajoute, dans des réalisations particulières, un sel d'argent ou de bismuth. Des exemples de réalisation spécifiques, non limitantes, comprennent des combinaisons de (i) minocycline, de triclosan, et d'un sel de bismuth, (ii) de minocycline, d'un composé chlorhexidine, et d'un sel de bismuth, et (iii) de minocycline, de chlorure de benzalkonium, et d'un sel de bismuth. L'invention concerne aussi des articles, notamment, mais pas seulement, des articles médicaux traités avec ou comprenant une combinaison d'antiseptique et d'antibiotique.
Modak Shanta M.
Sampath Lester A.
Tambe Suhas
Bereskin & Parr
The Trustees Of Columbia University In The City Of New York
LandOfFree
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