Method of screening for therapeutics for infectious diseases

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) C12Q 1/00 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2423879

The present invention relates to a method of screening for a host cell gene products which are useful as therapeutics for an infective diseases. This method comprises identifying genes which are differentially expressed in infected cells, and screening the differentially expressed gene products for immunogenicity.

Cette invention a trait à un méthode de criblage de produits géniques, dérivés de cellules hôtes, se révélant des plus utiles dans le cadre d'une thérapie de maladies infectieuses. La méthode consiste à identifier des gènes exprimés de manière différentielle dans des cellules infectées et à procéder à un criblage de ces produits géniques exprimés aux fins de la détermination de leur pouvoir antigénique.

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