Porous bioglass and preparation method thereof

A - Human Necessities – 61 – L

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Details

A61L 27/10 (2006.01) A61F 2/28 (2006.01) A61L 27/56 (2006.01)

Patent

CA 2574712

The invention relates to porous bioglass and to the preparation method thereof. More specifically, the invention relates to a solid, porous crystalline or partially-crystalline composition containing at least SiO2, Ca<SB>O</SB>, Na2O, and P2O5, comprising micropores and macropores. The invention is characterised in that: the pore ratio varies between 50 % and 80 %, preferably between 60 and 75 %, and is measured using the geometric method; the average diameter of the macropores varies between 100 and 1250 micrometers, preferably between 150 and 300 micrometers; the average diameter of the micropores is less than or equal to 5 micrometers; and the compression strength varies between 7 MPa and 70 MPa. The invention also relates to the method of preparing one such composition and to such a composition treated with a physiological liquid having an ionic composition similar to that of human plasma. The invention also relates to an implant which is made from one such composition.

La présente invention porte sur une composition cristalline ou partiellement cristalline poreuse massive comprenant au moins SiO2, CaO, Na2O, et P2O5, comprenant des micropores et des macropores, caractérisée en ce que : , le taux de porosité va de 50% à 80%, de préférence de 60 à 75%, mesuré par la méthode géométrique, , le diamètre moyen des macropores va de 100 à 1250 microns, de préférence de 150 microns à 300 microns, , le diamètre moyen des micropores est inférieur ou égal à 5 microns, , la résistance en compression va de 7 MPa à 70 MPa. Elle porte également sur le procédé de préparation d'une telle composition et sur une telle composition traitée par un liquide physiologique de composition ionique proche de celle du plasma humain. Elle porte encore sur un implant constitué d'une telle composition.

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