Intracellular targeting of molecules

A - Human Necessities – 61 – K

Patent

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Details

A61K 48/00 (2006.01) C12N 15/86 (2006.01) G01N 33/50 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2692886

The present invention provides methods for intracellular and/or nuclear targeting of an agent capable of specifically binding to syndecan-4. The present invention further provides methods for the modification of the intracellular and/or nuclear targeting of said agent, as well methods for identifying compounds capable of modifying the syndecan-4 delivery pathway. The present invention further provides experimental kits to perform the methods according to the invention.

La présente invention concerne des procédés de ciblage intracellulaire et/ou nucléaire d'un agent capable de se lier spécifiquement au syndécane-4. La présente invention concerne en outre des procédés permettant de modifier le ciblage intracellulaire et/ou nucléaire dudit agent, de même que des procédés permettant d'identifier des composés susceptibles de modifier la voie de distribution du syndécane-4. La présente invention concerne également des trousses expérimentales destinées à la mise en uvre des procédés selon l'invention.

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