C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/16 (2006.01) A61K 47/48 (2006.01)
Patent
CA 2738951
The present invention relates to novel transporter constructs of the generic formula (I) D I LLL x D m(LLL y D n)a and variants thereof. The present invention also refers to transporter cargo conjugate molecules, particularly of conjugates of the novel transporter constructs with a cargo moiety, e.g. proteins or peptides, nucleic acids, cytotoxic agents, organic molecules, etc. The present invention furthermore discloses (pharmaceutical) compositions comprising these conjugates and methods of treatment and uses involving such transporter constructs.
La présente invention concerne de nouvelles constructions de transporteurs de formule générique (I) DILLLxDm(LLLyDn)a et leurs variants. La présente invention concerne également des molécules de conjugués transporteur-charge, en particulier des conjugués des nouvelles constructions de transporteurs avec une fraction charge, par exemple des protéines ou des peptides, des acides nucléiques, des agents cytotoxiques, des molécules organiques, etc. La présente invention concerne en outre des compositions (pharmaceutiques) comprenant ces conjugués et des procédés de traitement et des utilisations impliquant ces constructions de transporteurs.
Kirby Eades Gale Baker
Xigen S.a.
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