Introduction of the wlds gene for prevention of axonal...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) A61P 25/28 (2006.01) C07H 21/00 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 19/00 (2006.01) C12N 15/09 (2006.01) C12N 15/63 (2006.01) C12N 15/85 (2006.01) C12N 15/861 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2462632

Polypeptides that can protect axons from axon degeneration and methods of use of the polypeptides are presented. Polynucleotides that can protect axons from axon degeneration and methods of use of the polynucleotides are presented. In addition, polynucleotides that encode the polypeptides referred to above are presented. Further, pharmaceutical compositions to treat conditions are presented.

L'invention concerne des polypeptides qui peuvent protéger les axones de la dégénérescence, ainsi que des méthodes d'utilisation de ces polypeptides. Elle concerne aussi des polynucléotides qui peuvent protéger les axones de la dégénérescence, ainsi que des méthodes d'utilisation de ces polynucléotides. Elle concerne encore des polynucléotides codant pour les polypeptides de l'invention. Elle concerne enfin des compositions pharmaceutiques destinées à traiter ces troubles.

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