Process for the production of malonic acid anhydride

C - Chemistry – Metallurgy – 07 – D

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C07D 305/10 (2006.01) C07C 51/54 (2006.01) C07D 319/06 (2006.01)

Patent

CA 2059698

ABSTRACT OF THE DISCLOSURE A process is disclosed for the safe production of malonic acid anhydride by ozonization of diketene in the presence of a carbonyl compound of the formula: Image (II) wherein R1 and R2 are the same or different and each represent hydrogen, an alkyl group, an alkoxy group or an aryl group. Malonic acid anhydride is a highly reactive intermediate reagent for the synthesis of numerous active ingredients for pharmaceutical agents, pesticides or dyes.

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