Benzoxazinone dopamine d4 receptor antagonists

Details Benzoxazinone dopamine d4 receptor antagonists Benzoxazinone dopamine d4 receptor antagonists

C - Chemistry, Metallurgy

07

D

C07D 417/14 (2006.01) A61K 31/535 (2006.01) A61K 31/675 (2006.01) C07D 265/36 (2006.01) C07D 413/06 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 417/12 (2006.01) C07F 9/6558 (2006.01)

Patent

CA 2253406

Compounds having formulae (I) or (II) wherein R1 and R2 are independently hydrogen or C1-C6 alkyl; X is N or CH; and R3 is phenyl, naphthyl, heteroaryl, substituted phenyl, substituted naphthyl or substituted heteroaryl, wherein each substituent is independently selected from halogen, C1-C6 alkoxy, C1-C6 alkyl, -CN, -CF3, or sulphonamido, and the pharmaceutically acceptable salts, esters, amides, and prodrugs thereof, are antagonists of dopamine D4 receptors.

La présente invention concerne des composés représentés par les formules générales (I) et (II), ainsi que leurs sels, esters, amides et promédicaments admis en pharmacie, lesquels composés sont des antagonistes des récepteurs de la dopamine D4. Dans ces formules générales R?1¿ et R?2¿ sont indépendamment hydrogène ou C¿1?-C¿6? alkyl. X est N ou CH. R?3¿ est phényl, naphtyl, hétéroaryl, phényl substitué ou hétéroaryl substitué, chacun des substituants appartenant indépendamment au groupe des halogène, C¿1?-C¿6? alcoxy, C¿1?-C¿6? alkyl, -CN, -CF¿3? ou sulphonamido.

Affiliated with

Also associated with

Rating

Benzoxazinone dopamine d4 receptor antagonists does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Benzoxazinone dopamine d4 receptor antagonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Benzoxazinone dopamine d4 receptor antagonists will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2054432