Non-sticky coatings with therapeutic agents for medical devices

Details Non-sticky coatings with therapeutic agents for medical devices Non-sticky coatings with therapeutic agents for medical devices

A - Human Necessities

61

L

A61L 31/02 (2006.01) A61L 31/10 (2006.01) A61L 31/16 (2006.01)

Patent

CA 2651574

A stent for delivering a therapeutic agent to body tissue of a patient and a method of making such a medical device are disclosed. The invention relates generally to a medical device such as an intravascular stent that is useful for delivering a therapeutic agent to the body tissue of a patient, and the method for making such a device. More particularly, in one embodiment the invention is directed to a stent having a tubular sidewall comprising a plurality of struts, in which the inner and outer surfaces of the struts are coated with different coating compositions. In another embodiment, a first coating composition comprising a therapeutic agent and a first polymer is disposed on the outer surface of the strut, while the inner surface is free of any coating composition.

L'invention concerne un stent pour délivrer un agent thérapeutique à un tissu du corps d'un patient ainsi qu'une méthode pour fabriquer un tel appareil médical. L'invention concerne en général un appareil médical tel qu'un stent intravasculaire qui est utile pour délivrer un agent thérapeutique au tissu du corps d'un patient, ainsi qu'une méthode pour fabriquer un tel appareil. Plus particulièrement, dans un mode de réalisation de l'invention, un stent présente un paroi latérale tubulaire qui comprend une pluralité d'étais dans lesquels les surfaces internes et externes sont enduites de différentes compositions de revêtement. Dans un autre mode de réalisation, une première composition de revêtement qui comprend un agent thérapeutique et un premier polymère est disposé sur la surface externe de l'étai, alors que la surface interne est dépourvue de composition de revêtement.

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