Glutathione-s-lower fatty acid derivative

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 5/037 (2006.01) C07K 1/02 (2006.01) C07K 5/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2060209

2060209 9116337 PCTABS00007 An S-(lower fatty acid)-substituted glutathione derivative of general formula (I), salts thereof, and production thereof, wherein R1 represents hydrogen, R3 represents hydrogen or optionally substituted lower alkyl, R4 represents optionally substituted lower alkoxy or optionally substituted amino, and n is 0 or 1, provided that when n is 1, R2 represents hydrogen, optionally substituted lower alkyl, or optionally substituted phenyl. These compounds can be advantageously used for treating hepatic disorders, because they have an excellent activity of inhibiting these disorders.

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