Novel tumor suppressor gene

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/11 (2006.01) A61K 31/711 (2006.01) A61K 35/00 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 14/82 (2006.01) C07K 16/32 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2389058

A novel tumor suppressor gene and a novel polypeptide having a 2-3 type zinc finger structure which is an amplification product of the tumor suppressor gene. The above gene and polypeptide are usable in diagnosing cancer, estimating the risk of carcinogenesis and gene therapy.

L'invention porte sur un nouveau gène suppresseur des tumeurs et sur un nouveau polypeptide ayant une structure de type zinc à 2-3 branches qui est un produit d'amplification du gène suppresseur des tumeurs. Le gène et le polypeptide précités peuvent être utilisés dans le diagnostic du cancer, les évaluations des risques de carcinogenèse et en thérapie génique.

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