Modified release formulations containing drug-ion exchange...

Details Modified release formulations containing drug-ion exchange... Modified release formulations containing drug-ion exchange...

A - Human Necessities

61

K

A61K 9/58 (2006.01) A61K 9/10 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2645855

A coated drug - ion exchange resin complex comprising a core composed of a drug complexed with a pharmaceutically acceptable ion-exchange resin is provided. The drug - ion exchange resin complex is in admixture with a release retardant. The coating contains a polyvinyl acetate polymer and a plasticizer. Methods of making and products containing this coated complex are described.

La présente invention concerne un complexe enrobé médicament ~ résine échangeuse d'ions comprenant un noyau composé d'un médicament complexé avec une résine échangeuse d'ions pharmaceutiquement acceptable. Le complexe médicament ~ résine échangeuse d'ions est en mélange avec un agent retardant la libération. L'enrobage contient un polymère d'acétate de polyvinyle et un plastifiant. L'invention concerne également des procédés de fabrication de ce complexe enrobé et des produits qui le contiennent.

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