Tetrahydroquinoline derivatives having selective activity...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 215/22 (2006.01) A61K 31/47 (2006.01) A61P 1/04 (2006.01) A61P 3/00 (2006.01) A61P 3/06 (2006.01) A61P 5/10 (2006.01) A61P 9/00 (2006.01) A61P 17/00 (2006.01) A61P 17/14 (2006.01) A61P 25/00 (2006.01) A61P 25/16 (2006.01) A61P 25/28 (2006.01) A61P 27/02 (2006.01) A61P 29/00 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) A61P 37/02 (2006.01) A61P 39/02 (2006.01) A61P 43/00 (2006.01) C07D 215/00 (2006.01) C07D 215/12 (2006.01) C07D 215/36 (2006.01)

Patent

CA 2346037

Compounds of Formula (1), where Y is a bivalent radical having Formula (2) or Formula (3) where o is an integer from 1 to 4, where the remaining symbols have the meaning described in the specification are selective agonists of RXR retinoid receptors.

On décrit des composés de formule (1) dans laquelle Y représente un radical divalent de formule (2) ou de formule (3) dans lesquelles o représente un entier compris entre 1 et 4, les autres symboles ayant la signification stipulée dans le descriptif. Ces composés sont des agonistes sélectifs des récepteurs de rétinoïde X.

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