Implantable device having reservoir with controlled release...

Details Implantable device having reservoir with controlled release... Implantable device having reservoir with controlled release...

A - Human Necessities

61

K

A61K 9/22 (2006.01)

Patent

CA 2573892

An implantable device (10) includes a body (12) defining a reservoir (14), and a head (24) provided at an end of the body (12) and closing the reservoir. The body (12) is made from a material impermeable to the medication while the head (24) is made from a permeable material adapted to release the medication from the reservoir to an implant site at a determinable rate. In one manufacture, the body (12) of the device is molded and includes a hole at a tip end; the head (24) is molded onto the body (12); the medication is injected into the device through the tip end hole; and the tip end is sealed. The portion of the device at which the medication is released is precisely fabricated in order to control release of the medication, and the reservoir is filled and then closed away from the area of medication permeability.

L'invention concerne un dispositif implantable (10) comprenant un corps (12) définissant un réservoir (14) et une tête (24) placée au niveau d'une extrémité du corps (12) et fermant le réservoir. Le corps (12) est conçu dans un matériau imperméable au médicament alors que la tête (24) est conçue dans un matériau perméable conçu pour libérer le médicament du réservoir dans un site d'implant à une vitesse pouvant être déterminée. Selon une fabrication, le corps (12) du dispositif est moulé et comprend un trou au niveau d'une extrémité en pointe; la tête (24) est moulée sur le corps (12); le médicament est injecté dans le dispositif par le biais du trou de l'extrémité en pointe; et l'extrémité en pointe est scellée. La partie du dispositif au niveau de laquelle le médicament est libéré est fabriquée de manière précise afin de commander la libération du médicament et le réservoir est rempli, puis fermé à distance de la zone de perméabilité au médicament.

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