C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/16 (2006.01) A61K 51/04 (2006.01)
Patent
CA 2644530
This invention relates to a method of imaging amyloid deposits and to styrylpyridine compounds, and methods of making radiolabeled styrylpyridine compounds useful in imaging amyloid deposits. This invention also relates to compounds, and methods of making compounds for inhibiting the aggregation of amyloid proteins to form amyloid deposits, and a method of delivering a therapeutic agent to amyloid deposits.
La présente invention concerne une méthode d'imagerie de dépôts amyloïdes et des styrylpyridines ainsi que les méthodes de fabrication de styrylpyridines radiomarquées pouvant être employées dans l'imagerie de dépôts amyloïdes. La présente invention concerne également des composés et des méthodes de fabrication de composés inhibant l'agrégation de protéines amyloïdes responsables de la formation de dépôts amyloïdes, ainsi qu'une méthode de libération d'un agent thérapeutique au niveau des dépôts amyloïdes.
Kung Hank F.
Kung Mei-Ping
Marks & Clerk
The Trustees Of The University Of Pennsylvania
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