Glycemic control, diabetes treatment, and other treatments...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/445 (2006.01) A61K 31/27 (2006.01) A61K 31/473 (2006.01) A61K 31/55 (2006.01) A61P 3/10 (2006.01) A61K 31/155 (2006.01) A61K 31/166 (2006.01) A61K 31/4545 (2006.01) A61K 33/30 (2006.01)

Patent

CA 2704728

There is disclosed a method for gjycemic control of a patient having a disease selected from the group consisting of type 1 diabetes mellitus, type 2 diabetes mellitus, impaired glucose tolerance, hyperglycemia, and postprandial hyperglycemia, said method comprising administering to a patient in need thereof a pharmaceutical composition comprising an acetyl cholinesterase inhibitor compound. There is further disclosed a method for reducing HbA1c concentrations as a measure of glycemic control, comprising administering to a patient in need thereof a pharmaceutical composition comprising an acetyl cholinesterase inhibitor compound. Lastly, there is disclosed a pharmaceutical formulation for daily administration comprising an acetyl cholinesterase inhibitor, from about 5 mg to about 15 mg of loratadine and optionally from about 5 mg to about 16 mg of elemental zinc.

La présente invention a pour objet un procédé de contrôle de la glycémie d'un patient souffrant d'une maladie choisie dans le groupe constitué du diabète sucré de type 1, du diabète sucré de type 2, d'une altération de la tolérance au glucose, d'une hyperglycémie et d'une hyperglycémie postprandiale, ledit procédé comprenant l'administration à un patient en ayant besoin d'une composition pharmaceutique renfermant un composé inhibiteur de l'acétylcholinestérase. L'invention a en outre pour objet un procédé de réduction des concentrations de HbA1c comme mesure du contrôle de la glycémie, comprenant l'administration à un patient en ayant besoin d'une composition pharmaceutique renfermant un composé inhibiteur de l'acétylcholinestérase. Finalement, l'invention concerne une formulation pharmaceutique pour une administration quotidienne renfermant un inhibiteur de l'acétylcholinestérase, d'environ 5 mg à environ 15 mg de loratadine et éventuellement d'environ 5 mg à environ 16 mg de zinc élémentaire.

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