Treatment of diseases using nalmefene and its analogs

A - Human Necessities – 61 – K

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A61K 31/485 (2006.01)

Patent

CA 2579378

The use of nalmefene and its analogs for treatment of conditions or diseases that are not mediated through opiate receptors is disclosed. Such condition and diseases include viral infections such as hepatitis B and C, organ damage, septic shock, various cancers and conditions associated with over production of superoxide, TNF-.alpha. and iNOS.

La présente invention concerne l'utilisation de nalméfène et de ses analogues pour traiter des pathologies ou des maladies dont la médiation n'est pas assurée par des récepteurs opioïdes. De telles pathologies ou maladies comprennent des infections virales, comme l'hépatite B et C, une lésion d'organe, un choc septique, divers cancers et des pathologies associées à la production excessive de superoxyde, TNF-a et iNOS.

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