Compositions and methods relating to culturing neural stem...

C - Chemistry – Metallurgy – 12 – N

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C12N 5/00 (2006.01) C12N 5/02 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01)

Patent

CA 2555376

The present invention encompasses methods and compositions for enhancing the growth of neural stem cells. Methods for modulating MHC molecule expression on a neural stem cell (NSC) are also included in the invention. Figure 1 is a graph depicting the proliferation of BMSCs in BMSC medium (DMEM-low glucose, 10% lot tested fetal bovine serum) or NSC medium (DMEM-F12, N2-Supplement, EGF 20 ng/ml, bFGF 10 ng/ml, heparin 8 ug/ml, penicillin-streptomycin).

La présente invention concerne des méthodes et des compositions favorisant le développement de cellules souches neurales. L'invention englobe également des méthodes de modulation de l'expression de la molécule CMH sur une cellule souche neurale.

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