External preparation for skin

Details External preparation for skin External preparation for skin

A - Human Necessities

61

K

A61K 8/33 (2006.01) A61K 8/97 (2006.01) A61Q 19/02 (2006.01)

Patent

CA 2548123

The invention aims at providing external preparations for skin which inhibit excessive melanin formation and thus exhibit skin-whitening effect while keeping the natural whiteness and which function as substantial lightening preparations. The invention relates to an external preparation for skin which contains both at least one member selected from among centaureidin (5,7- dihydroxy-3,6-dimethoxy-2-(5-hydroxy-4- methoxyphenyl)-4H-1-benzopyran-4-one), 5,7-dihydroxy-3,6,8- trimethoxy-2-(3,4,5-trihydroxyphenyl)-4H-1-benzopyran-4- one, 3,5-diethoxy-6,7-dimethoxy-2-(5-ethoxy-4-methoxyphenyl)-4H-1-benzopyran-4- one, 5,6-dihydroxy-3,7-dimethoxy-2-(5- hydroxy-2,4-dimethoxyphenyl)-4H-1- benzopyran-4-one and salts thereof, and at least one member selected from among 4-n-butylresorcinol and salts thereof.

L'invention porte sur des préparations pour la peau à usage externe qui inhibent la formation excessive de mélanine et déploient par conséquent un effet de blanchiment cutané tout en préservant la blancheur naturelle, lesquelles préparations sont utilisées pour obtenir un éclaircissement sensible de la peau. L'invention concerne une préparation pour la peau à usage externe qui contient à la fois un élément choisi parmi la centaurédine (5,7-dihydroxy-3,6-dimethoxy-2-(5-hydroxy-4-methoxyphényl)-4H-1-benzopyran-4-one), 5,7-dihydroxy-3,6,8-trimethoxy-2-(3,4,5-trihydroxyphényl)-4H-1-benzopyran-4-one, 3,5-diethoxy-6,7-dimethoxy-2-(5-ethoxy-4-methoxyphényl)-4H-1-benzopyran-4-one, 5,6-dihydroxy-3,7-dimethoxy-2-(5-hydroxy-2,4-dimethoxyphényl)-4H-1-benzopyran-4-one et des sels de ces dernières, et au moins un élément choisi parmi un 4-n-butyresorcinol et des sels de ce dernier.

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