Self-emulsifying formulations of lipophilic drugs

Details Self-emulsifying formulations of lipophilic drugs Self-emulsifying formulations of lipophilic drugs

A - Human Necessities

61

K

A61K 38/13 (2006.01) A61K 9/107 (2006.01) A61K 9/48 (2006.01) A61K 47/14 (2006.01) A61K 47/22 (2006.01)

Patent

CA 2221145

Self-emulsifying pharmaceutical pre-concentrate compositions comprising: (a) a lipophilic medicinal compound, (b) d-alpha-tocopheryl polyethylene glycol 1000 succinate (TPGS), and (c) a lipophilic phase as well as pharmaceutical compositions comprising such pre-concentrates in combination with a sufficient amount of water to produce a stable emulsion.

L'invention concerne des compositions pharmaceutiques préconcentrées auto-émulsifiantes contenant: (a) un médicament lipophile, (b) du succinate de d-alpha-tocophéryl polyéthylène glycol 1000 et (c) une phase lipophile, ainsi que des compositions pharmaceutiques comprenant de tels préconcentrés en combinaison avec une quantité suffisante d'eau pour produire une émulsion stable.

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