Gdf3 propeptides and related methods

Details Gdf3 propeptides and related methods Gdf3 propeptides and related methods

C - Chemistry, Metallurgy

12

N

C12N 15/18 (2006.01) A61K 38/18 (2006.01) A61K 47/48 (2006.01) C07K 14/475 (2006.01) C07K 14/495 (2006.01) C07K 19/00 (2006.01) C12N 15/12 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2572330

In certain aspects, the present invention provides compositions and methods for regulating body weight, in particular, for treating obesity and obesity- associate disorders. The present invention also provides methods of screening compounds that modulate activity of GDF3. The compositions and methods provided herein are also useful in treating diseases associated with abnormal activity of GDF3.

Dans certains aspects, cette invention concerne des compositions et des méthodes destinées à réguler le poids corporel, notamment, à traiter l'obésité et des troubles liés à l'obésité. Ladite invention a aussi pour objet des méthodes de criblage de composés qui modulent l'activité de GDF3. Ces compositions et ces méthodes sont utilisées dans le traitement de maladies liées à une activité anormale de GDF3.

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