Canine erythropoietin gene and recombinant protein

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/63 (2006.01) A01N 37/18 (2006.01) C07K 14/505 (2006.01) C07K 16/00 (2006.01) C12N 1/20 (2006.01) C12N 15/85 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2326384

One aspect of the present invention is an isolated nucleic acid molecule encoding canine erythropoietin. The present invention also relates to an isolated canine erythropoietin protein or polypeptide. Another aspect of the present invention is a method for providing erythropoietin therapy to a dog or a cat including administering recombinant canine erythropoietin to a dog or a cat in need of erythropoietin therapy in an amount sufficient to increase production or reticulocytes and red blood cells in the dog or cat.

Dans l'un de ses aspects, l'invention concerne une molécule isolée d'acide nucléique codant une érythropoïétine canine. L'invention concerne encore une protéine ou polypeptide isolé d'érythropoïétine canine, de même qu'un procédé d'apport d'une thérapie à base d'érythropoïétine à un chien ou à un chat, ce procédé consistant à administrer une érythropoïétine canine recombinée à un chien ou à un chat nécessitant un telle thérapie, en dose suffisante pour augmenter la production des réticulocytes et des globules rouges chez ce chien ou ce chat.

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