C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07H 21/00 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C12N 1/19 (2006.01) C12N 5/10 (2006.01) C12N 5/16 (2006.01) C12N 5/22 (2006.01) C12N 15/09 (2006.01) C12N 15/63 (2006.01) C12N 15/66 (2006.01) C12N 15/74 (2006.01) C12N 15/79 (2006.01) C12P 21/00 (2006.01) C12P 21/02 (2006.01) C12P 21/08 (2006.01) C12Q 1/00 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) G01N 33/567 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2415460
The invention relates to a method with a wide range of applications, for identifying chemical compounds that modulate G-protein-coupled receptors by means of novel hybrid G-proteins with an extremely broad receptor specificity and an extremely high expression. The invention also relates to chemical compounds that can be identified by a method of this type.
La présente invention concerne un procédé à large champ d'application permettant d'identifier des composés chimiques qui modulent des récepteurs couplés à la protéine G, au moyen de nouvelles protéines G hybrides présentant une très large spécificité de récepteur et une très grande expression. La présente invention concerne également des composés chimiques qui peuvent être identifiés à l'aide d'un tel procédé.
Aventis Pharma Deutschland Gmbh
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Sanofi-Aventis Deutschland Gmbh
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