Whooping cough vaccine

Details Whooping cough vaccine Whooping cough vaccine

C - Chemistry, Metallurgy

12

N

C12N 15/31 (2006.01) A61K 31/10 (2006.01) C07K 14/235 (2006.01) C07K 19/00 (2006.01) C12N 1/21 (2006.01) C12N 15/62 (2006.01) C12N 15/70 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2086888

The invention relates to acellular vaccines being effective against whooping cough and is based on a functional component of the fimbriae of Bordetella pertussis i.e. the actual adhesin molecule being a "minor" component in the fimbriae. The vaccines according to the invention have the advantage that both they may induce an effective immune respons against all B.pertussis strains and - most likely - also against Bordetella parapertussis being the second important causative agent of whooping cough. Further, the vaccines may also be used for veterinary applications, to protect against Bordetella bronchiseptica infections.

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