Use of intraputaminal infused glial cell-line derived...

Details Use of intraputaminal infused glial cell-line derived... Use of intraputaminal infused glial cell-line derived...

A - Human Necessities

61

K

A61K 38/18 (2006.01) A61P 25/16 (2006.01)

Patent

CA 2516857

A method of treating Parkinson's disease in humans is disclosed, wherein glial cell-line derive neurotrophic factor (GDNF) is chronically administered directly to one or both putamen of a human in need of treatment thereof. In one aspect of the present invention the GDNF is infused directly into one or both putamen through one or more indwelling intraparenchymal brain catheters connected to an implantable pump.

L'invention porte sur une méthode de traitement de la maladie de Parkinson chez l'homme, cette méthode consistant à administrer en permanence le facteur neurotrophique dérivé d'une lignée de cellules gliales (GDNF) directement vers un ou deux putamens du patient nécessitant ce traitement. Selon un mode d'exécution de cette invention le GDNF est administré directement dans un ou deux putamens par un ou plusieurs cathéters intra-parenchymateux installés à demeure dans le cerveau et connectés à une pompe implantable.

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