5-ht3 receptor modulators, methods of making, and use thereof

Details 5-ht3 receptor modulators, methods of making, and use thereof 5-ht3 receptor modulators, methods of making, and use thereof

C - Chemistry, Metallurgy

07

D

C07D 519/00 (2006.01) A61K 31/55 (2006.01) A61P 1/00 (2006.01) A61P 1/08 (2006.01) A61P 25/00 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2724449

Novel 5-HT3 receptor modulators are disclosed. These compounds are used in the treatment of various disorders, including chemotherapy-induced nausea and vomiting, post-operative nausea and vomiting, and irritable bowel syndrome. Methods of making these compounds are also described in the present invention.

La présente invention concerne de nouveaux modulateurs de récepteur 5-HT3. Ces composés sont utilisés dans le traitement de différents troubles, y compris la nausée et le vomissement induits par une chimiothérapie, la nausée et le vomissement post-opératoires, et le syndrome du côlon irritable. La présente invention concerne en outre des procédés de préparation de ces composés.

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