Chimeric capsid proteins and uses thereof

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 19/00 (2006.01) C07K 14/005 (2006.01) C12N 15/62 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2454882

The present invention encompasses chimeric capsid proteins, nucleic acids encoding such proteins and capsids containing chimeric capsid proteins. Methods of making the chimeric capsid proteins, the nucleic acids that encode such proteins and capsids that contain chimeric capsid proteins are also encompassed within the scope of the invention. The invention further encompasses the use of the chimeric capsid proteins to produce protein elements and to present the elements for use in structure-function studies, for use as therapeutic factors and for other purposes. Other embodiments of the invention will be apparent to those skilled in the art from consideration of the specification and practice of the invention disclosed herein. It is intended that the specification and examples be considered as exemplary only.

La présente invention concerne des protéines de capsides chimériques, des acides nucléiques codant de telles protéines et des capsides contenant des protéines de capsides chimériques. L'invention concerne également des procédés permettant de constituer ces protéines de capsides chimériques, ces acides nucléiques codant de telles protéines et ces capsides contenant de telles protéines de capsides chimériques. L'invention concerne aussi l'utilisation des protéines de capsides chimériques pour produire des éléments de protéines et pour proposer ces éléments pour l'étude des rapports entre fonctions et structures, pour les utiliser comme facteurs thérapeutiques et pour d'autres fins. Les experts en la matière en déduiront aisément d'autres modes de réalisation de l'invention, les spécifications et exemples n'étant donnés qu'à titre indicatif.

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