Soluble ctla4 mutant molecules and uses thereof

Details Soluble ctla4 mutant molecules and uses thereof Soluble ctla4 mutant molecules and uses thereof

A - Human Necessities

61

K

A61K 38/16 (2006.01) C07H 21/04 (2006.01) C07K 14/705 (2006.01) C12N 15/00 (2006.01) C12N 15/01 (2006.01) C12N 15/09 (2006.01) C12N 15/12 (2006.01) C12N 15/63 (2006.01) C12N 15/70 (2006.01) C12N 15/79 (2006.01) C12P 21/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2278771

This invention provides soluble CTLA4 mutant molecules which bind with greater avidity to the CD86 antigen than wildtype CTLA4.

La présente invention concerne des molécules mutantes CTLA4 solubles qui se lient plus avidement à l'antigène CD86 qu'au CTLA4 de type sauvage CTLA4.

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