Process for the production of 10beta-h-steroids

C - Chemistry – Metallurgy – 07 – J

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C07J 21/00 (2006.01) C07J 1/00 (2006.01) C07J 31/00 (2006.01) C07J 33/00 (2006.01) C07J 41/00 (2006.01) C07J 43/00 (2006.01) C07J 51/00 (2006.01)

Patent

CA 2084313

Compounds of general formula (III), in which A and B together stand for an additional bond and D stands for a hydrogen atom or B and D together stand for an additional bond and A stands for a hydrogen atom and Y and Y' each stand for a protect- ed keto group and R1 and R4 have the meaning given in the description, can be reduced with an electropositive metal, with- out destroying the aromatic system and the 5,6 double bond, to compounds of general formula (IIa), which can be converted to compounds of general formule (Ia) or (Ib) which are useful in the synthesis of antigestagens.

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