The application of potassium 2-(1-hydroxypentyl)-benzoate...

A - Human Necessities – 61 – K

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A61K 31/192 (2006.01) A61K 9/08 (2006.01) A61K 9/107 (2006.01) A61K 9/14 (2006.01) A61K 9/20 (2006.01) A61K 9/48 (2006.01) A61P 25/28 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2730154

The present invention discloses the use of potassium 2-(.alpha.- hydroxypentyl) benzoate in the manufacture of medica-ments for preventing, relieving or treating senile dementia diseases or symptom, and for relieving oxidative stress injury in brain tissue, increasing neural function of choline, protecting neuron and/or raising the content of brain nerve growth factor The present invention also discloses a pharmaceutical composition comprising potassium 2- (.alpha.- hydroxypentyl) benzoate in prophylactically or therapeutically effective dose, optionally, a pharmaceutically acceptable carrier and/or adjuvant

La présente invention a pour objet lutilisation de 2-(a-hydroxypentyl)benzoate dans la fabrication de médicaments destinés à la prévention, au soulagement ou au traitement de la maladie ou des symptômes de la démence sénile ou au soulagement dune lésion de stress oxydatif du tissu cérébral, à laugmentation de la fonction neurale de la choline, à la protection des neurones et/ou à laugmentation de la teneur en facteur de croissance des cellules nerveuses du cerveau. La présente invention concerne également une composition pharmaceutique renfermant du 2-(a-hydroxypentyl)benzoate de potassium dans une dose efficace dun point de vue prophylactique ou thérapeutique, éventuellement, un support et/ou un adjuvant pharmaceutiquement acceptable.

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