Apparatus and method of mixing materials in a sterile...

Details Apparatus and method of mixing materials in a sterile... Apparatus and method of mixing materials in a sterile...

B - Operations, Transporting

01

F

B01F 5/06 (2006.01)

Patent

CA 2146090

An apparatus for mixing a particulate material into a liquid includes a pair of variable volume receptacles interlinked by a communication passage. A combined volume of liquid and particulate material is received within the variable volumes, and the volume of the variable volumes is alternately reduced and to force the materials back and forth through the connection passage. The variable volumes may be formed from a rigid walled cylinder having a free floating piston therein, and the piston and inner diameter may have a tight, sealed gap therebetween. To load the piston into the cylinder without effecting the seals, a load apparatus may be used to depress the seals inwardly of the piston and align the piston in the cylinder.

L'invention porte sur un appareil servant à mélanger une substance particulaire à un liquide. L'appareil comporte une paire de récipients à volume variable interreliés par un passage de communication. Les récipients à volume variable reçoivent un volume combiné de liquide et de substance particulaire, puis le volume des récipients est alternativement réduit pour forcer les substances d'un récipient à l'autre par le biais du passage de communication. Les récipients à volume variable peuvent être formés à partir d'un cylindre à paroi rigide ayant un piston libre à l'intérieur. De plus, le piston et la circonférence interne peuvent comprendre un écart serré et scellé entre eux. Pour introduire le piston dans le cylindre sans endommager les joints, un appareil d'introduction peut être utilisé pour déprimer les joints vers l'intérieur du piston et pour aligner ce dernier dans le cylindre.

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