Practical in vitro sialylation of recombinant glycoproteins

C - Chemistry – Metallurgy – 12 – P

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C12P 21/00 (2006.01) C12N 9/10 (2006.01)

Patent

CA 2278178

This invention provides methods for practical in vitro sialylation of glycoproteins, including recombinantly produced glycoproteins. The methods are useful for large-scale modification of sialylation patterns.

La présente invention concerne des procédés efficaces de sialylation in vitro de glycoprotéines, parmi lesquelles on trouve des glycoprotéines produites de manière recombinée. Les procédés s'utilisent pour modifier à grande échelle des configurations de sialylation.

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