C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 295/13 (2006.01) A61K 31/395 (2006.01) C07C 211/58 (2006.01) C07D 211/14 (2006.01) C07D 211/22 (2006.01) C07D 211/46 (2006.01) C07D 211/58 (2006.01) C07D 213/72 (2006.01) C07D 213/74 (2006.01) C07D 215/38 (2006.01) C07D 239/42 (2006.01) C07D 243/08 (2006.01) C07D 295/125 (2006.01) C07D 317/58 (2006.01) C07D 401/04 (2006.01) C07D 405/00 (2006.01) C07D 409/06 (2006.01) C07D 451/02 (2006.01)
Patent
CA 2200083
The invention concerns novel compounds of general formula (I) and pharmacologically acceptable salts thereof, A, B, Z, R1, R2, R3 and m having the definitions given in the description; methods of producing said compounds; and pharmaceutical compositions containing said compounds. The compounds are valuable neurokinin (tachykinin) antagonists.
L'invention concerne de nouveaux composés de formule générale (I) et leurs sels pharmaceutiquement acceptables. Dans la formule (I), A, B, Z, R?1¿, R?2¿, R?3¿ et m ont la notation mentionnée dans la description. L'invention concerne également leurs procédés de fabrication, ainsi que des compositions pharmaceutiques contenant ces composés. Ces composés constituent de précieux antagonistes de la neurokinine (tachykinine).
Briem Hans
Dollinger Horst
Jung Birgit
Schnorrenberg Gerd
Speck Georg
Boehringer Ingelheim Kg
Fetherstonhaugh & Co.
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