Process of preparing esters of penicillanic acid sulfoxide

Details Process of preparing esters of penicillanic acid sulfoxide Process of preparing esters of penicillanic acid sulfoxide

C - Chemistry, Metallurgy

07

D

C07D 499/10 (2006.01) C07D 499/00 (2006.01)

Patent

CA 2354019

A new synthesis of penicillanic sulfoxide acid ester is claimed. The synthesis starts with 6-amino penicillanic acid and proceeds through conversion to a bromide via diazotization, esterification, reduction of the bromide, and oxidation of the resulting penicillanic ester.

La présente invention concerne une nouvelle synthèse d'ester de sulfoxyde d'acide pénicillanique. On commence la synthèse avec de l'acide 6-amino pénicillanique et on la continue par une conversion en bromure via la diazotation, l'estérification la réduction du bromure puis l'oxydation de l'ester d'acide pénicillanique obtenu.

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