Thienopyridine derivatives and use thereof as hsp90 modulators

C - Chemistry – Metallurgy – 07 – D

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C07D 495/04 (2006.01) A61K 31/4365 (2006.01)

Patent

CA 2599826

The invention relates to novel thienopyridine derivatives of formula (I), where R1, R2, R3 and Y have the meanings given in claim 1, which are HSP90 inhibitors and can be used for the production of a medicament for the treatment of diseases in which the inhibition, regulation and/or modulation of HSP90 play a role.

L'invention concerne de nouveaux dérivés de thiénopyridine de formule (I), dans laquelle R1, R2, R3 et Y ont les significations indiquées dans la revendication 1, lesdits dérivés étant des inhibiteurs de la HSP90 et pouvant être utilisés pour produire un médicament destiné au traitement de maladies dans lesquelles l'inhibition, la régulation et/ou la modulation de la HSP90 jouent un rôle.

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