Substituted cinnamic acid guanidides, a process for their...

Details Substituted cinnamic acid guanidides, a process for their... Substituted cinnamic acid guanidides, a process for their...

C - Chemistry, Metallurgy

07

C

C07C 279/22 (2006.01) A61K 31/16 (2006.01) A61K 31/4409 (2006.01) A61K 49/00 (2006.01) C07D 213/65 (2006.01) C07D 213/70 (2006.01)

Patent

CA 2182062

Substituted cinnamic acid guanidides, a process for their preparation, their use as medicaments or diagnostic agents and medicaments comprising them Compounds of the formula I (see formula I) are described in which at least one of the substituents R(1), R(2), R(3), R(4) and R(5) is a nitrogen-containing heterocyclic radical. They are outstanding cardiovascular therapeutic agents. They are obtained by reaction of a compound II (see formula II) with guanidine.

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