Total synthesis of salinosporamide a and analogs thereof

Details Total synthesis of salinosporamide a and analogs thereof Total synthesis of salinosporamide a and analogs thereof

C - Chemistry, Metallurgy

07

D

C07D 487/14 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2717715

The present application relates to certain compounds and to methods for the preparation of certain compounds that can be used in the fields of chemistry and medicine. Specifically, described herein are methods for the preparation of various compounds and intermediates, and the compounds and intermediates themselves. More specif-ically, described herein are methods for synthesizing Sali-nosporamide A and its analogs that includes forming a compound of formula (VIII).

La présente invention concerne certains composés et des procédés pour la préparation de certains composés qui peuvent être utilisés dans les domaines de la chimie et de la médecine. Particulièrement, l'invention concerne des procédés pour la préparation de divers composés et intermédiaires, et les composés et intermédiaires eux-mêmes. Plus particulièrement, l'invention concerne des procédés de synthèse de Salinosporamide A et de ses analogues, ce qui comprend la fabrication d'un composé de formule (VIII).

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