C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 215/54 (2006.01) A61K 31/137 (2006.01) A61P 25/16 (2006.01) C07C 215/52 (2006.01) C07C 215/60 (2006.01)
Patent
CA 2410660
Described are cyclohexylamine derivatives of Formula (I), Formula (II) or Formula (III) and their pharmaceutically acceptable salts thereof. The compounds are antagonists of NMDA receptor channel complexes useful for treating cerebral vascular disorders such as, for example, cerebral ischemia, cardiac arrest, stroke, and Parkinson's disease. The substituents are described in the specification.
L'invention concerne des dérivés de cyclohexylamine représentés par les formules (I), (II) ou (III) avec leurs sels pharmaceutiquement acceptables. Ces composés sont des antagonistes des complexes du canal des récepteurs de NMDA (N-Méthyl D-Aspartate) qui sont utiles pour traiter les troubles cérébro-vasculaires comme l'ischémie cérébrale, l'arrêt cardiaque, l'accident vasculaire cérébral et la maladie de Parkinson. Les substituants sont présentés dans le descriptif.
Deorazio Russell Joseph
Nikam Sham Shridhar
Scott Ian Leslie
Sherer Brian Alan
Wise Lawrence David
Sim & Mcburney
Warner-Lambert Company
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