Human ion channels

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61P 25/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12N 15/11 (2006.01) C12N 15/86 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2393538

The present invention provides novel ion channel polypeptides and polynucleotides which identify and encode them. In addition, the invention provides expression vectors, host cells and methods for their production. The invention also provides methods for the identification of ion channel agonists/antagonists, useful for the treatment of human diseases and conditions.

La présente invention concerne des polypeptides de canaux ioniques et des polynucléotides qui les identifient et les codes. L'invention concerne également des vecteurs d'expression, des cellules hôtes et des procédés se rapportant à leur obtention. L'invention concerne enfin des procédés d'identification d'agonistes/antagonistes de canaux ioniques, convenant particulièrement pour le traitement d'états pathologiques et d'affections de l'homme.

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