Use of phenalkylamines

Details Use of phenalkylamines Use of phenalkylamines

C - Chemistry, Metallurgy

07

C

C07C 225/16 (2006.01) A61K 31/135 (2006.01) A61K 31/137 (2006.01) A61K 31/138 (2006.01) A61K 31/275 (2006.01) A61K 31/277 (2006.01) C07C 217/22 (2006.01) C07C 255/24 (2006.01)

Patent

CA 2126518

Use of compounds of the formula (see formula I) wherein one of R1 and R2 is C1-7-alkyl and the other is C1-7-alkyl or C2-6-alkenyl-methyl, L is C1-11-alkylene or C2-11-alkenylene optionally bonded to the phenyl group via an O atom or L is 1,4-phenylene, n = 0 or, where L contains an O atom, n = 0 or 1; Q is C1-7-alkyl, C2-10-alkenyl or a group of formula Q': Image R is H, halogen, CF3, CN or NO2, R3 and R4 are H, C1-4-alkyl or halogen and R5 is H or, where R is H, H or halogen, and their pharmaceutically acceptable acid addition salts for the manufacture of cholesterol-lowering medicaments, as well as novel compounds falling under formula I.

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