New process for the preparation of morphinans

Details New process for the preparation of morphinans New process for the preparation of morphinans

C - Chemistry, Metallurgy

07

D

C07D 489/09 (2006.01) C07D 491/18 (2006.01)

Patent

CA 2269910

A process for the preparation of 14-alkoxyindolomorphinans and 14- alkoxybenzofuranomorphinans is disclosed. The process facilitates the preparation of a large variety of 14-alkoxy substituted indolomorphinans and benzofuranomorphinans in which a 3-hydroxy substituent is present.

L'invention a trait à un procédé de préparation de 14-alcoxyindolomorphinanes et de 14-alcoxybenzofuranomorphinanes. Ce procédé rend plus aisée la préparation d'une grande variété d'indolomorphinanes et de benzofuranomorphinanes à substitution 14-alcoxy dans lesquelles est présent un substituant 3-hydroxy.

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