Mass-based toxin assay and substrates therefor

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/37 (2006.01)

Patent

CA 2526476

An assay for a metalloprotease comprises (i) combining a test compound with a substrate, wherein the protease reacts with the substrate to form a product; and (ii) detecting presence of the metalloprotease by measuring the mass of the product.

L'invention concerne un dosage pour une métalloprotéase qui consiste : (i) à combiner un composé d'essai avec un substrat, la protéase réagissant avec le substrat afin de former un produit ; et (ii) à détecter la présence de la métalloprotéase en mesurant la masse du produit.

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