N-arylheteroarylalkyl 1-cycloalkyl-imidazol-2-one compounds...

Details N-arylheteroarylalkyl 1-cycloalkyl-imidazol-2-one compounds... N-arylheteroarylalkyl 1-cycloalkyl-imidazol-2-one compounds...

C - Chemistry, Metallurgy

07

D

C07D 401/14 (2006.01) A61K 31/44 (2006.01) C07D 401/06 (2006.01)

Patent

CA 2143192

A class of N-arylheteroarylalkyl 1-cycloalkyl-imidazol-2-one compounds is described for use in treatment of circulatory disorders such as hypertension and congestive heart failure. Compounds of particular interest are angiotension II antagonists of formula (A), wherein A is selected from (a), (b), (c), (d), (e) and (f); wherein each of R1, R2 and R3 is independently selected from hydrido, alkyl, alkoxy, halo, hydroxy, carboxyl, alkoxycarbonyl, formyl and acetyl; wherein R7 is hydrido; R8 is alkyl; wherein R9 is an acidic group selected from COOH and (g); or a stereoisomer or a tautomer thereof or a pharmaceutically- acceptable salt thereof.

Affiliated with

Also associated with

Rating

N-arylheteroarylalkyl 1-cycloalkyl-imidazol-2-one compounds... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with N-arylheteroarylalkyl 1-cycloalkyl-imidazol-2-one compounds..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and N-arylheteroarylalkyl 1-cycloalkyl-imidazol-2-one compounds... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2070464