A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/045 (2006.01) A61K 31/59 (2006.01) A61K 45/06 (2006.01)
Patent
CA 2451039
A method of inhibiting the hyperproliferation of malignant or neoplastic cells, comprising treating the cells with an antiproliferative amount of 1- alpha, 24(S)-dihydroxyvitamin D2. The method also includes the co- administration of cyotoxic agents with the 1-alpha, 24(S)-dihydroxyvitamin D2. The figure illustrates the preparative steps for the synthesis of 24- hydroxyvitamin D2.
La présente invention concerne une technique d'inhibition de l'hyperprolifération de cellules malignes ou néoplasiques, qui consiste à traiter ces cellules avec une quantité antiproliférative de 1-alpha, 24(S)-dihydroxyvitamine D¿2?. Cette technique consiste aussi à co-administrer des agents cytotoxiques avec cette 1-alpha, 24(S)-dihydroxyvitamine D¿2?. La figure illustre les étapes de préparation de la synthèse de 24-hydroxyvitamine D¿2?.
Bishop Charles W.
Knutson Joyce C.
Mazess Richard B.
Strugnell Stephen A.
Bone Care International Inc.
Torys Llp
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