Therapeutic composition with a botulinum neurotoxin

Details Therapeutic composition with a botulinum neurotoxin Therapeutic composition with a botulinum neurotoxin

A - Human Necessities

61

K

A61K 38/48 (2006.01) A61K 47/36 (2006.01)

Patent

CA 2578250

The present invention pertains to pharmaceutical compositions which comprise a botulinum neurotoxin from Clostridium botulinum, the neurotoxin being free of the complexing proteins naturally present in the botulinum neurotoxin complex or being chemically modified or being modified by genetic manipulation. Moreover the pharmaceutical compositions of the instant invention have good stability and are advantageously formulated free of human serum albumin.

Cette invention concerne des compositions pharmaceutiques qui contiennent une neurotoxine botulique tirée de Clostridium botulinum et exempte des protéines complexantes naturellement présentes dans le complexe de neurotoxine botulique, ou une neurotoxine botulique chimiquement modifiée ou modifiée par manipulation génétique. Ces compositions pharmaceutiques possèdent en outre une bonne stabilité et il est avantageux de les formuler sans albumine sérique humaine.

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